Nearly one in five people using pre-exposure prophylaxis (PrEP) get it through the nation’s largest telehealth PrEP provider. Researchers analyzed records from more than half a million people—predominantly young men—who contacted MISTR about PrEP between 2018 and 2025. Over half did not proceed after their initial intake survey or did not follow up with the required clinician video visit or lab tests. Of the 162,422 people who received a prescription, three quarters had not pre-viously used PrEP, and more than a third were uninsured. The study confirmed the well-known disparity in PrEP use: 51% were white, 25% were Latino and 12% were Black. Telehealth PrEP use increased over time, from 204 people in 2019 to 110,068 in 2024. Looking at the bigger picture, the proportion of all national PrEP users who accessed it via MISTR’s telePrEP program rose from less than 1% in 2019 to 19% in 2024. These findings suggest that telePrEP is “a critical part of HIV prevention infrastructure” in the United States, the study authors concluded.